ABOUT US  |  CONTACT US  |  RSS  |  ARCHIVE  |  2023-12-05  |  UPDATED: 1402/09/13 - 17:50:1 FA | AR | PS | EN
Factbox: Israeli genocidal war on Gaza Ė What has happened so far?             Israeli attacks on Gaza kill 700 Palestinians in 24 hours            Iran FM: USí supportive policies encourage Zionist regime to continue massacre of civilians in Gaza             Everything in Gaza is at breaking point: ICRC             US sends deadly bunker buster bombs to Israel for Gaza war            Israel pulls back negotiating team from Qatar, as truce talks hit Ďdead endí             Israeli attack kills over 100 Palestinians in Gaza refugee camp             Erdogan says Netanyahu, íthe butcher of Gazaí, must be tried in ICC            Israel kills 2 IRGC military advisors in strike on Syria             Taliban De-Persianizing Afghanistan Culture: Roots and Ramifications             Afghanistan: Armed attack in Shia-populated region of Herat 5 killed             Israelis Stealing Body Organs of Palestinians Killed in War: European Monitor            Resistance vows to give Israel harsher response if Gaza war resumes: Iran             íThis is a war on children,í UNICEF warns after Israel resumes bombing Gaza             Political figures criticize UN report for alleged Ďwhitewashingí of Taliban, demand accountability            


DATE PUBLISHED: 1400/10/21 - 15:00:5
VISIT: 14022
SHARE WITH YOUR FRIENDS

In a first, man gets heart transplant from genetically altered pig

A US man with terminal heart disease was implanted with a genetically modified pig heart in a first-of-its-kind surgery, and three days later the patient is doing well, his doctors reported on Monday.

The surgery, performed by a team at the University of Maryland Medicine, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools.

If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.

"Weíve never done this in a human and I like to think that we, we have given him a better option than what continuing his therapy would have been," Dr. Bartley Griffith, who surgically transplanted the pig heart into the patient, said in a video interview provided by the university.

"But whether itís a day, week, month, year, I donít know," Griffith added.

For 57-year-old David Bennett of Maryland, the heart transplant was his last option.

"It was either die or do this transplant. I want to live. I know itís a shot in the dark, but itís my last choice," Bennett said a day before his surgery, according to a statement released by the university.

To move ahead with the experimental surgery, the university obtained an emergency authorization from the US Food and Drug Administration on New Yearís Eve through its compassionate use program.

"The FDA used our data and data on the experimental pig to authorize the transplant in an end-stage heart disease patient who had no other treatment options," said Dr. Muhammad Mohiuddin, who heads the Universityís program on xenotransplantation - transplanting animal organs into humans.

About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to organdonor.gov.

Bennettís genetically modified pig heart was provided by Revivicor, a regenerative medicine company based in Blacksburg, Virginia. On the morning of the surgery, the transplant team removed the pigís heart and placed it into a special device to preserve its function until the surgery.

Pigs have long been a tantalizing source of potential transplants because their organs are so similar to humans. A hog heart at the time of slaughter, for example, is about the size of an adult human heart.

Other organs from pigs being researched for transplantation into humans include kidneys, liver and lungs.

Prior efforts at pig-to-human transplants have failed because of genetic differences that caused organ rejection or viruses that posed an infection risk. Scientists have tackled that problem by editing away potentially harmful genes.

In the heart implanted in Bennett, three genes previously linked with organ rejection were "knocked out" of the donor pig, and six human genes linked with immune acceptance were inserted into the pig genome.

Researchers also deleted a pig gene to prevent excessive growth of the pig heart tissue.

The work was funded in part with a $15.7 million research grant to evaluate Revivicorís genetically-modified pig hearts in baboon studies.

In addition to the genetic changes to the pig heart, Bennett received an experimental anti-rejection drug made by Kiniksa Pharmaceuticals based in Lexington, Mass.

(Source: Reuters)

 

LINK: https://www.ansarpress.com/english/26015


TAGS:






*
*

*



SEE ALSO

Report : Spinal implant helps a person with advanced Parkinsonís disease walk without falling


Over $250 million of counterfeit HIV treatments sold


Pandemic babies may have slight development lag Ė study


Omicron 2nd most contagious virus known to mankind Ė US doctor


MSF reports basic medical needs of Afghans are not being met


Miami Doctor Dies After Getting Pfizer COVID-19 Vaccine, Reports Say


Iranian and Afghan medical universities sign MoU to strengthen relations


British coronavirus vaccine: Human trials to include 10,000


Oxford-based pharmatech company uses artificial intelligence to find drug against COVID-19


Coronavirus: WHO warns against íimmunity passportsí for recovered patients





VIEWED
MOST DISCUSSED




POLL

Modi, Merkel Discuss Afghanistan, Radicalisation And Terrorism

SEE RESULT


LAST NEWS

How the Zionist entity sought to make colonial myth of íterra nulliusí a reality

Factbox: Israeli genocidal war on Gaza Ė What has happened so far?

Israeli attacks on Gaza kill 700 Palestinians in 24 hours

Iran FM: USí supportive policies encourage Zionist regime to continue massacre of civilians in Gaza

Everything in Gaza is at breaking point: ICRC

US sends deadly bunker buster bombs to Israel for Gaza war

Israel pulls back negotiating team from Qatar, as truce talks hit Ďdead endí

Israeli attack kills over 100 Palestinians in Gaza refugee camp

Erdogan says Netanyahu, íthe butcher of Gazaí, must be tried in ICC

Israel kills 2 IRGC military advisors in strike on Syria

Taliban De-Persianizing Afghanistan Culture: Roots and Ramifications

Afghanistan: Armed attack in Shia-populated region of Herat 5 killed

Israelis Stealing Body Organs of Palestinians Killed in War: European Monitor

Resistance vows to give Israel harsher response if Gaza war resumes: Iran

íThis is a war on children,í UNICEF warns after Israel resumes bombing Gaza

Political figures criticize UN report for alleged Ďwhitewashingí of Taliban, demand accountability

Huge explosion rocks Kabul

Hamas says made deal to extend Gaza truce by 2 days

Lack of Access to Information Increased By 32 Percent

Pentagon chief visits Ukraine to reassure Kiev amid concerns over US support

UN rights chief calls for end to Israeli killing of Gazaís people at schools, shelters

From hospitals to cemeteries, Israel bombing both living and dead in Gaza

Weapons allegedly found in Gazaís al-Shifa Hospital Ďrearrangedí by Israeli army, CNN suggests

Israel committing ígenocideí against Gazaís health system: Palestinian minister

Iran does not seek spread of Israelís war on Gaza, but US approach makes it possible

Pro-Palestine demonstrations continue in Britain and France

Israeli regime should stand trial at ICC: Turkish president

Elon Musk, caving in to Zionist lobby, warns to criminalize pro-Palestine content

Saudi Arabia detains worshipers for supporting Gaza, praying for Palestine at holy sites: Report

Israel killed 12,000 Palestinians, including 5,000 children, since October 7

UN: Food-water Ďpractically non-existentí in Gaza

íRobust Measuresí Keep US Aid From Benefiting Taliban: Miller

Pakistan Claims Attacks in Pakistan Linked to Afghans

UNHCR: Forced return of Afghans from Pakistan deepens humanitarian crisis

Vatican: Pope to meet Palestinians, families of captives

Elon Musk under fire for supporting Palestine

Congresswoman Omar unveils resolution to block US arms sale to Israel

Bahrain crown prince condemns Hamasí al-Aqsa Storm Operation

AOHR UK: Parliamentís vote to continue the genocidal war by Israel confirms its participation in this crime

Israel launches military operation against Gazaís Shifa Hospital


MEDICAL NEWS


ANSAR PRESS ©  |  ABOUT US  |  CONTACT US  |  MOBILE VERSION  |  LINKS  |  DESIGN: Negah Network Co.
All right reserved. Use this website by mentioning the source (link) is allowed. ›—ś‘ź«Ś «یš —š ی šŕŠ»šŌ«š