ABOUT US  |  CONTACT US  |  RSS  |  ARCHIVE  |  2024-10-03  |  UPDATED: 1403/06/01 - 19:53:2 FA | AR | PS | EN
Talibans new law bans womens voices and faces             Iranian police shut down two illegal centers affiliated with German government             All of President Pezeshkians ministerial picks win parliaments vote of confidence             Wheres Bangladesh Heading after Popular Uprising?            Western Kabul residents say Taliban has failed to ensure security after bombing             Algerian Boxer Khelif files complaint over online harassment after gender row             Federalism in Afghanistan: Opportunities and Challenges             Formation of the Federalist Assembly of Afghanistan             Israel launches missile attack on outskirts of Damascus, killing Syrian civilians             UK national scandal: 20,000 mental health patients raped, sexually assaulted in NHS care             Three US troops killed, dozens injured in drone attack in Syria             Trump says NATO will not come to rescue if US attacked             Ukraine beset by $40m fraud in arms procurement amid war with Russia            US approves sale of F-16 jets to Turkey after Ankara ratifies Swedens NATO membership             UNSC to meet to discuss ICJ ruling on Israeli genocide in Gaza            


DATE PUBLISHED: 1400/10/11 - 23:11:3
VISIT: 3499
SHARE WITH YOUR FRIENDS

Mixing Pfizer, AstraZ COVID-19 shots with Moderna gives better immune response: UK study


A teenager receives a dose of a vaccine against COVID-19 in a tent at Copacabana beach in Rio de Janeiro, Brazil, on December 31, 2021. (Photo by AFP)

A major British study into mixing COVID-19 vaccines has found that people had a better immune response when they received a first dose of AstraZeneca or Pfizer-BioNTech shots followed by Moderna nine weeks later, according to the results on Monday.

"We found a really good immune response across the board..., in fact, higher than the threshold set by Oxford-AstraZeneca vaccine two doses," Matthew Snape, the Oxford professor behind the trial dubbed Com-COV2, told Reuters.

The findings supporting flexible dosing will offer some hope to poor and middle income countries which may need to combine different brands between first and second shots if supplies run low or become unstable.

"I think the data from this study will be especially interesting and valuable to low- and middle-income countries where theyre still rolling out the first two doses of vaccines," Snape said.

"Were showing...you dont have to stick rigidly to receiving the same vaccine for a second dose...and that if the program will be delivered more quickly by using multiple vaccines, then it is okay to do so."

If the AstraZeneca-Oxford vaccine is followed by a Moderna or Novavax shot, higher antibodies and T-cell responses were induced versus two doses of AstraZeneca-Oxford, according to researchers at the University of Oxford.

The study of 1,070 volunteers also found that a dose of the Pfizer-BioNTech (PFE.N), (22UAy.DE) vaccine followed by a Moderna shot was better than two doses of the standard Pfizer-BioNTech course.

Pfizer-BioNTech followed by Novavax induced higher antibodies than the two-dose Oxford-AstraZeneca schedule, although this schedule induced lower antibody and T-cell responses than the two-dose Pfizer-BioNTech schedule.

No safety concerns were raised, according to the Oxford University study published in the Lancet medical journal.

Many countries have been deploying a mix and match well before robust data was available as nations were faced with soaring infection numbers, low supplies and slow immunization over some safety concerns.

Longevity of protection offered by vaccines has been under scrutiny, with booster doses being considered as well amid surging cases. New variants, including Delta and Omicron, have now increased the pressure to speed up vaccination campaigns.

Blood samples from participants were tested against the Wild-Type, Beta and Delta variants, researchers of the Com-COV2 study said, adding that vaccines efficacy against the variants had waned, but this was consistent across mixed courses.

Deploying vaccines using technology from different platforms - like Pfizer and Modernas mRNA, AstraZenecas viral vector and Novavaxs protein-based shot - and within the same schedule is new.

The results may inform new approaches to immunization against other diseases, he said.

The study also found that a first dose of the AstraZeneca-Oxford vaccine followed by any of the other candidates in the study generated a particularly robust response, consistent with findings in June.

The study was designed as a so-called "non-inferiority" study - the intent is to demonstrate that mixing is not substantially worse than the standard schedules - and compares the immune system responses to the gold-standard responses reported in previous clinical trials of each vaccine.

 

(Source: Reuters)

 

LINK: https://www.ansarpress.com/english/25526


TAGS:






*
*

*



SEE ALSO

Israel launches missile attack on outskirts of Damascus, killing Syrian civilians


Ukraine beset by $40m fraud in arms procurement amid war with Russia


US approves sale of F-16 jets to Turkey after Ankara ratifies Swedens NATO membership


UNSC to meet to discuss ICJ ruling on Israeli genocide in Gaza


Gazas major health facility collapses amid Israeli attacks: MSF


Americans to redeploy nuclear weapons in UK amid fears of WW3


Yemen directly hits US warship with ballistic missile


Turkish lawmakers open debate over Swedens NATO membership


Palestinian Islamic Jihad: Al-Maghazi operation proved defeat of Israeli regime in Gaza war


Pakistan Army Kills Seven Terrorists Near Afghan Border





VIEWED
MOST DISCUSSED




POLL

Modi, Merkel Discuss Afghanistan, Radicalisation And Terrorism

SEE RESULT


LAST NEWS

Sudan: The Forgotten War

Talibans new law bans womens voices and faces

Iranian police shut down two illegal centers affiliated with German government

All of President Pezeshkians ministerial picks win parliaments vote of confidence

Wheres Bangladesh Heading after Popular Uprising?

Western Kabul residents say Taliban has failed to ensure security after bombing

Algerian Boxer Khelif files complaint over online harassment after gender row

Federalism in Afghanistan: Opportunities and Challenges

Formation of the Federalist Assembly of Afghanistan

Israel launches missile attack on outskirts of Damascus, killing Syrian civilians

UK national scandal: 20,000 mental health patients raped, sexually assaulted in NHS care

Three US troops killed, dozens injured in drone attack in Syria

Trump says NATO will not come to rescue if US attacked

Ukraine beset by $40m fraud in arms procurement amid war with Russia

US approves sale of F-16 jets to Turkey after Ankara ratifies Swedens NATO membership

UNSC to meet to discuss ICJ ruling on Israeli genocide in Gaza

Taliban: Afghanistan Does Not Have Formal Border With Pakistan

Gazas major health facility collapses amid Israeli attacks: MSF

Americans to redeploy nuclear weapons in UK amid fears of WW3

Biden makes history: 1st sitting US president sued for complicity in genocide

Trump walks out of courtroom during closing arguments of Carrolls attorney

US: 3 dead in shooting at Texas apartment complex

US-UK aggression against Yemen risks expansion of war: Iran

Yemen directly hits US warship with ballistic missile

Hamas has self-reliantly opposed the three giant intelligence agencies of the world!

President Raeisi calls for UN reform, says body unable to end Gaza genocide

Pedram: The Abduction of Hazara and Tajik Women Recalls the Crimes of Abdur Rahman

Special envoys from G7 countries discuss Afghanistan in London meeting

Turkish lawmakers open debate over Swedens NATO membership

UN agency says over half a million Palestinians face catastrophic hunger in Gaza

Palestinian Islamic Jihad: Al-Maghazi operation proved defeat of Israeli regime in Gaza war

European support for Israel damaging energy security on the continent, report says

Pakistan Army Kills Seven Terrorists Near Afghan Border

Israel kills at least 190 people in Khan Younis in 24 hours

UNAMA report: 49 Hazara community members killed in Afghanistan in three months

Indias Modi inaugurates Hindu temple on site of razed mosque ahead of elections

US 2024 election: DeSantis drops out of Republican presidential race, backs Trump

Survivors of Russian charter flight crash transferred to Kabul

Irans anti-terror strikes clear message to certain recipients: Foreign Ministry

Ethnic mass killings in one Sudan city last year left up to 15,000 dead: UN report


MEDICAL NEWS


ANSAR PRESS  |  ABOUT US  |  CONTACT US  |  MOBILE VERSION  |  LINKS  |  DESIGN: Negah Network Co.
All right reserved. Use this website by mentioning the source (link) is allowed. Ԑ یی